I think Drew was confused with Eds feeling for Jade at first with him pashing, and sleeping over in her bed when drunk etc and laughing about it with his mates the next day but it was really started the week that Matt and Ed went on attack towards Drully. (Matt had been bitchy about Tully for a few weeks about being over-emotional and about her feelings for Drew)
Ed said Drew made him look the fool by saving Jade with his showdown win, after Ed had just put her up for nominations instead of Tim.
Tim told Drew that Matt and Ed wanted to confront Drully at family dinner about their emotional cheating but chickened out last minute, and Ed also upset Tully that night with their drunken fight about not trusting Drew because he wasn't on their side (he was Team Tim)
Drew told Ben he tried to hang out with Ed in the gym after Caleb and Matt etc were gone but Ed really just wanted to obsess about Tim..so Drew got bored with Ed.
He didn't like the Jaded relationship, with Ed giving Jade his 'lucky rock' after their date etc and didnt believe he was really into Jade from previous conversations, so was probably going to leave Jade heartbroken.
Drew also saw Ed nominate him in face to face (when Drew hadnt nominated him that week) and made a fuss about Tim and Drew nominating Jade..so I'm sure Drew had enough to be annoyed with Ed at times, even though I heard Drew actually praise Ed to his face a couple times, and to Boog in those last few weeks.Boog and Drew were talking to each other, praising Ed about his football days, and also said it was shame he got injured etc